Across and Down

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There are 10 clues with the answer 'DETRIMENTALLY'
# CLUE
1.
Tried with difficulty to get guys to agree, causing harm (13)
2.
Tell my trained modification is adversely affected (13)
3.
Stupidly tried using brain, in a way that's harmful (13)
4.
Tried somehow to get chaps to agree in a harmful way
5.
Unhealthily tired, wandering in mind (13)
6.
Tried out with the mind, causing loss? (13)
7.
Dreadfully tired men add up score in a disadvantageous way (13)
8.
Tried working out in the head - in a way it could be harmful (13)
9.
Red mitten upset friend in a hurtful way (13)
10.
Red mitten upset friend in a hurtful way