| MUTATION | A change in the structure of a gene (8) |
| BENIGN | Abnormal change in the structure of an organ (6) |
| LIMERICK | There once was a chief executive and artistic director in the structure, who were part of the city o |
| PARALLAX | The observed displacement of an object caused by a change in the observer's point of view (8) |
| HEADWIND | When did a change in the weather slow down the craft (8) |
| LOCUS | From "place", the site or scene of any happening or crime; the position of a gene on a chromosome; a set of mathematical points; a passage in writing; or, whereabouts generally (5) |
| REPUBLIC | The ___, Socratic dialogue written by Plato examining the nature and structure of a just society (8) |
| NERVEEND | In biology, terminal structure of a cord consisting of bundles of fibres (5,3) |
| ALFRESCO | One missing coal fires for a change in the open (8) |
| GARDENIA | Flowering plant requiring a change in the drainage (8) |
| HEREDITY | A gene is a unit of this (8) |
| PINECONE | The seed-producing structure of a pine tree (4,4) |
| AIRFRAME | Structure of a plane without the engine |
| ULCERATE | Become sore after structure of a lecture changed (8) |
| HOMEOTIC | Relating to or being a gene producing a usually major shift in structural development |
| JOIST | A beam used to support part of the structure of a building (5) |
| ALLELE | One of the possible forms of a gene located in the same place on a chromosome |
| PERUTZ | Max Ferdinand ___, Austrian-born British biochemist; shared the 1962 Nobel Prize in Chemistry for studies in the structure of haemoglobin (6) |
| DISSECTION | The act of cutting open and examining the structure of a dead animal or plant (10) |
| SHIFT | 19th-century chemise made of homespun cotton or linen; a movement of the hand on a violin's fingerboard; or, a change in the direction of true wind in sailing (5) |