| SETTLEDOWN | Agree, depressed, and establish roots (6,4) |
| RESETTLE | Establish roots elsewhere |
| ANCESTRY | A northern church's attempt to establish roots |
| TIETHEKNOT | Thus connect painter with craft and establish union? |
| DANISHBLUE | Like Hamlet, depressed, and possibly crackers with it |
| BROKENDOWN | Penniless by noon, depressed and worn out |
| DISPIRITED | Depressed and, swallowing hard stuff, expired (10) |
| DOWNLOADED | Acquired from the net when depressed and drunk (10) |
| SETTLE | To let get set and establish it (6) |
| UPSHOP | Push pesto, freshly made, and establish a business (3,2,4) |
| SET | Push pesto, freshly made, and establish a business (3,2,4) |
| LOSTANDFOUND | See bear and establish location of missing property (4-3-5) |
| MOPE | I object about work and become depressed and listless (4) |
| LOWCOUNTRIES | Depressed and down with Clare around railway in Holland and Belgium (3,9) |
| DOWNHILL | Depressed and unwell after his first skiing event (8) |
| UNDERTHEWEATHER | Depressed and hurt, we need heart treatment |
| BELOW | Feel depressed and down |
| DOWNPOUR | Big fall makes you depressed and reportedly broke |
| BLUEGREEN | Of mixed appearance, being both depressed and naive (4-5) |
| BLUE | Depressed - and perhaps livid (4) |