| PADUCAH | City in Kentucky, US, at the confluence of the Ohio and Tennessee Rivers |
| CAIRO | City on the Nile - or at the confluence of the Ohio and Mississippi rivers (5) |
| LOUISVILLE | Largest city in Kentucky, US |
| TENNESSEE | River of the south-eastern US, the longest tributary of the Ohio (9) |
| CHATTANOOGA | US city in SE Tennessee on the Tennessee River (11) |
| AKRON | City on the Ohio and Erie Canal |
| BAKERSFIELD | City in California, US, at the southern end of the San Joaquin valley associated with the oil indust |
| DAYTON | The sixth largest city in Ohio and the county seat of Montgomery County |
| REINSTATES | Brings back the teaching of religion in Alabama and Tennessee? (10) |
| KEYWEST | Island in the Straits of Florida associated with Ernest Hemingway and Tennessee Williams |
| CUMBERLANDGAP | Pass in the Appalachian Mountains, used by pioneers to reach Kentucky and Tennessee |
| EUSTON | In school, put us at the end of the line (6) |
| AMERICANEMBASSY | Diplomatic mission for us at the end of autumn in place of overseas reps (8,7) |
| WABASH | Largest northern tributary of the Ohio river, forming a 200-mile (320 km) section of the Indiana-Illinois border (6) |
| ERLANGER | Parisian financier (1832-1911) after whom a bank and a city in Kentucky was named (8) |
| ALLEGHENY | River running through New York and Pennsylvania that is a principal tributary of the Ohio River |
| ERIE | A member of an Iroquoian people formerly living on the south shore of Lake Erie in northern Ohio and northwest Pennsylvania and western New York. |
| SUNISALEE | With Simone Biles and Hezly Rivera, one of the five Golden Girls (gold medal-winning gymnasts of Team USA at the 2024 Paris Olympics): 2 wds. |
| LABOUR | You"ll find work belonging to us at the end of the science room (6) |
| DULUTH | Port in Minnesota, US, at the west end of Lake Superior (6) |
