| RIOBAMBA | City in central Ecuador |
| COTOPAXI | Volcanic peak in central Ecuador (8) |
| SANGAY | Active volcano of central Ecuador (6) |
| CORDOBA | In which city in central Argentina was a university founded in 1613? (7) |
| CERRODEPASCO | A city in central Peru, in the Andes; one of the highest cities in the world (5,2,5) |
| MACON | City in central Georgia or east-central France |
| TEOTIHUACAN | Ancient city in central Mexico (c. 200-750) in which the pyramids of the Sun and Moon were built |
| NAGANO | A city in central Japan on Honshu; host city of the 1998 Winter Olympics (6) |
| UPPSALA | City in central Sweden that was the royal headquarters in the 13th Century (7) |
| BENDIGO | City in central Victoria, Australia that was founded in 1851 after the discovery of gold (7) |
| XUCHANG | City in central China, capital in the Han Dynasty (7) |
| MARCH | A city in central Scotland on the River Tay, location of the assassination of James I of Scotland in 1437 (5) |
| ELOBEID | City in central Sudan; scene of the defeat of a British and Egyptian army by the Mahdi in 1883 (2,5) |
| KANDY | City in Central Province, Sri Lanka, designated a UNESCO World Heritage site in 1988 |
| MANAGUA | Capital city in Central America (pop 1 million), hit by a major earthquake in 1972 (7) |
| THEBES | City in central Greece which played an important part in Greek mythology (6) |
| ETIENNE | Saint- _, city in central France in the Loire department (7) |
| SIENA | Cathedral city in central Italy (pop 55,000), with a university founded in 1472 (5) |
| TOLEDO | City in central Spain nicknamed the City of the Three Cultures (6) |
| FRESNO | City in central California in the San Joaquin Valley (6) |