| POWELL | Colin, George W. Bush's first Secretary of State (6) |
| COLINPOWELL | Gulf War General and Secretary of State for George W Bush's first term (5,6) |
| ARISCHER | George W. Bush's first press secretary |
| CASTLE | Barbara ___, First Secretary of State from 1968-70 (6) |
| ANGELA | ___ Eagle, Labour's Shadow First Secretary of State 2015-16 (6) |
| MELLOR | David -, 1979-97 Conservative MP for Putney; first Secretary of State for National Heritage in 1992 (6) |
| ALHAIG | Ron Reagan's first secretary of state |
| ODESSA | George HW Bush's first Texas home |
| CASTRO | Fidel ___, First Secretary of the Communist Party of Cuba from 1965-2011 (6) |
| DUBCEK | Alexander --, First Secretary of the Communist Party of Czechoslovakia (6) |
| AUGHTS | Period of George W. Bush's presidency |
| CHENEY | Dick, George W. Bush's vice president (6) |
| ELAINE | Chao of George W. Bush's cabinet |
| MINETA | Secretary in both Clinton's and George W. Bush's cabinet |
| GENERALHAIG | Ronald Reagan's first Secretary of State or the commander of the British Expeditionary Force during much of the First World War |
| SPOTTY | George W. Bush's English springer spaniel |
| UNITER | George W. Bush's self-description, during the 2000 campaign |
| ALGORE | George W Bush's rival for the 2001 presidential elections (2,4) |
| HAIG | Alexander ___, Reagan's first secretary of state |
| VANCE | Carter's first secretary of state |
