| ASTUDYINSCARLET | Debut novel of Arthur Conan Doyle's Sherlock Holmes and Dr. Watson, published in 1887 (1,5,2,7) |
| SIGN | The _ of the Four: written in 1890, the second of Arthur Conan Doyle's Sherlock Holmes novels (4) |
| REDHEADED | Eponymous League investigated in the second of Sir Arthur Conan Doyle's Sherlock Holmes short stories (3-6) |
| MYCROFT | Older brother of Sir Arthur Conan Doyle's Sherlock Holmes (7) |
| MALONE | Edward, narrator of Arthur Conan Doyle's science fiction novel The Lost World (6) |
| ATLANTIS | Mythical setting of Arthur Conan Doyle's 'The Maracot Deep' |
| STUDY | A - in Scarlet; Sir Arthur Conan Doyle's first novel to feature Sherlock Holmes and Dr Watson (5) |
| SCARLET | A Study in -; novel in which Arthur Conan Doyle introduces Sherlock Holmes and Dr Watson (7) |
| ARTHUR | Forename of a novelist who, in his 1887 work of fiction A Study in Scarlet, created the crime-solving duo Sherlock Holmes and Dr Watson (6) |
| THEHOUNDOFTHE | Sherlock Holmes and Dr Watson investigate a crime on the moors in Conan Doyle's ... Baskervilles (3, |
| CRAZYRICHASIANS | Debut novel of Singaporean-born US author Kevin Kwan (2013), adapted to the big screen in 2018 (5,4,6) |
| MORIARTY | Professor _, archenemy of Conan Doyle's Sherlock Holmes (8) |
| REICHENBACHFALLS | Location of the final altercation between Sherlock Holmes and Professor Moriarty in The Final Problem by Sir Arthur Conan Doyle (11,5) |
| ELEMENTARY | TV series in which Jonny Lee Miller and Lucy Liu play Sherlock Holmes and Watson (10) |
| SPECKLEDBAND | "The Adventure of the ... ... ", tale by Arthur Conan Doyle featuring the characters Sherlock Holmes and Helen Stoner (8,4) |
| SENSIBILITY | Sense and ___ bestselling debut novel of Jane Austen published in 1811 that revolves around three sisters as they come of age |
| FINAL | The -- Problem, short story by Arthur Conan Doyle featuring Sherlock Holmes and Professor Moriarty (5) |
| DORAN | George H. ___ Company (onetime publisher of Arthur Conan Doyle, P. G. Wodehouse, and Virginia Woolf) |
| SHERLOCK | Mr. Holmes, detective creation of Arthur Conan Doyle (8) |
| ADLER | Irene -; character portrayed by Rachel McAdams in the 2009 film Sherlock Holmes and its 2011 sequel (5) |
