| CRUX | E Latin name for the Southern Cross (4) |
| ARGO | Formerly a large constellation in the southern hemisphere between Canis Major and the Southern Cross. |
| AREA | ___ X (setting for the Southern Reach Trilogy) |
| LYRA | What is the Latin name for the constellation Lyre (4) |
| URSA | ___ Major, Latin name for the constellation that contains the Big Dipper asterism (4) |
| GENU | Latin name for the knee (4) |
| NUNC | ___ Dimittis, the Latin name for the Canticle of Simeon |
| CRUXAUSTRALIS | Another name for the constellation the Southern Cross |
| DIXIE | Informal name for the Southern states of the US, from the title of a song written by Daniel Decatur Emmett in 1859 (5) |
| FIVESTAR | Of excellent quality, like the number of bodies in the Southern Cross? (4-4) |
| MOPOKE | Popular alternative name for the Southern Boobook Owl |
| AURORAAUSTRALIS | Another name for the southern lights (6,9) |
| MUSCA | A small constellation in the Southern Hemisphere, lying between the Southern Cross and Chamaeleon (5) |
| BETACRUCIS | The second-brightest star in the Southern Cross, also called Mimosa (4,6) |
| SAMOA | Island nation whose flag features the Southern Cross |
| RUMELIA | Turkish name, used from the 15th century onwards, for the southern Balkan regions of the Ottoman Empire |
| DELTA | Large US airline named for the southern region of the Mississippi River |
| CSA | Grp. represented by the Southern Cross |
| TOBACCO | Cash crop for the southern American colonies |
| SEDGE | Kind of iris for the southern border (5) |