| BOONE | Frontiersman who crossed the Appalachians |
| SITTINGBULL | After the 1876 victory over Generalcuster in the Montana territory at The Battle of the Littlebighorn, Sioux Chief who crossed the border into Canada with 5000 Lakota people and took refuge until 1881 |
| HEYERDAHL | Norwegian anthropologist who crossed the Pacific from Peru to the Tuamotu Islands of French Polynesia on the balsa raft Kon-Tiki in 1947 (4,9) |
| THOR | Norwegian anthropologist who crossed the Pacific from Peru to the Tuamotu Islands of French Polynesia on the balsa raft Kon-Tiki in 1947 (4,9) |
| WESTVIRGINIAN | Of a US state bounded by the Appalachians to the east and the Ohio River to the west (4,9) |
| HANNIBAL | General who crossed the Alps with elephants and defeated the Romans (8) |
| CHARLESBLONDIN | French tightrope walker and acrobat who crossed the gorge below Niagara Falls on a tightrope for the first time in 1859 |
| GAIUSJULIUSCAESAR | Full name of the Roman emperor who crossed the Rubicon in 49BC |
| MAGELLAN | Portuguese navigator who crossed the Pacific |
| MOSES | Religious figure who crossed the Red Sea |
| FINISHER | One who's crossed the line (8) |
| MTS | The Andes and the Appalachians, for example: Abbr. |
| PILGRIM | Forbidding plump women chasing back speaker who crossed the Atlantic (7,7) |
| LINDBERGH | US aviator who crossed the Atlantic in 1927; Charles ... (9) |
| BLONDIN | Charles, French tightrope walker who crossed the Niagara Falls (7) |
| BETSY | Pioneer of song who "crossed the wide mountains with her lover Ike" |
| ALLEGHENY | The --- Mountains of the Appalachians extend from northern Pennsylvania to southwestern Virginia (9) |
| ALLEGHENIES | Range within the Appalachians, rich in coal and timber |
| SMOKY | Great ___ Mountains (section of the Appalachians) |
| SMOKIES | Range of the Appalachians |
