| LENAHORNE | Her musical career started at age 16 at the Cotton Club |
| DEWLAP | Friend we would back may, at a stretch, be 16 at the front? (6) |
| BOOKSHOP | Gets a ticket for over-16 at The Works, for example (8) |
| ANDREA | Tenor Bocelli who released the album "Duets" to celebrate thirty years of his musical career (October, 2024) |
| TINEAR | It may quash dreams of a musical career |
| TYRA | Supermodel Banks whose TV career started on The Fresh Prince of Bel-Air |
| DRE | Dr. whose career started in the World Class Wreckin' Cru |
| OPRAH | She lists George Winston and Charlotte Church among her musical favorites |
| SHANIA | Twain who's making her musical mark |
| SERENADES | Dee snares them with her musical accomplishments (9) |
| CAITLINMORAN | Journalist whose career started with Melody Maker, and whose Twitter feed was included in a 2014 A-level English syllabus |
| LENA | Horne who started at the Cotton Club |
| ELLINGTON | American bandleader whose orchestra played at the Cotton Club, Duke ... |
| DUKEELLINGTON | Frequent performer at the Cotton Club (1991, 1992, 2001, 2010, 2015) |
| ETHEL | Waters who debuted "Stormy Weather" at the Cotton Club in 1933 |
| CABCALLOWAY | Renowned bandleader at the Cotton Club |
| STORMYWEATHER | Song written in 1933 and first performed by Ethel Waters at The Cotton Club in Harlem (6,7) |
| LEXI | Golfer ___ Thompson, who had her first LPGA tournament win at age 16 |
| JACQUELINEDUPRE | Cellist who debuted at London's Wigmore Hall at age 16 |
| JUSTINBIEBER | Pop singer who released the #1 album My World 2.0 in 2010 at age 16: 2 wds. |