| CARNABYSTREET | In the 1960s in London this road became famous as a centre of popular fashion industry (7,6) |
| PAPHOS | Village in SW Cyprus famous as a centre of Aphrodite worship (6) |
| LILNASX | American rapper whose single Old Town Road became the longest-running number one in US chart history in 2019 (3,3,1) |
| APPEARED | Animal carrying fruit at end of road became visible (8) |
| SEAMAN | In 1805 this Newfoundland became famous as part of Lewis and Clark's expedition across the United States. He was the only animal to complete the journey. |
| DOG | After starring in hundreds of TV spots between 1997-2000, a Chihuahua named Gidget became famous as the "Taco Bell ___" |
| WEBB | Who (Harry ___) became famous as Cliff Richard? (4) |
| LANDONTHEMOON | What travel agents to the stars set out to do in the 1960s in Montes Alpes, for instance? (4,2,3,4) |
| LILIANBAYLIS | Who was a theatrical manager and the founder of the Old Vic as a centre of Shakespearean productions? |
| OLDROSE | Won in Tralee in the 1960s in the pink? (3,4) |
| REDROADFLATS | High-rise housing built in the 1960s in Balornock district of Glasgow, fully demolished by 2015 (3,4,5) |
| PORTLAND | Oregon city, noted as a centre for organised crime in the 1940s and '50s and of counterculture in the 1960s and '70s (8) |
| POUNDNOTE | Presumably in London this was the cost in hard cash of hit record? (5,4) |
| LSD | Drug that NASA gave to dolphins in the 1960s in an attempt to communicate with them |
| DALLAS | Texas city noted as a centre of the oil industry (6) |
| YOUNGSTOWN | City in Ohio, US formerly known as a centre of steel production (10) |
| ABBEY | Sir Edward Elgar conducted the LSO at the opening of the famous recording studio on this road - but it took the Beatles to make it really famous |
| DUNKIRK | Seaport of northern France, famous as a scene of evacuation of Allied troops in World War II (7) |
| OREO | Cookie brand that opened a "Twists Lab" pop-up in London this month |
| MILAN | Italian city known as a centre of fashion (5) |