| MARGIN | Initially, Ricky Gervais featured in the most important side (6) |
| BABY | ___ Shark (song featured in the most-viewed YouTube video ever) |
| FLIPSIDE | The reverse or less important side (4,4) |
| PRIORY | Abbey? It's not in the most important position (6) |
| ATTHESHARPEND | Involved in the most important part of a venture (2,3,5,3) |
| BONHAM | Who played Princess Margaret in the most recent season of The Crown? (6,6) |
| OPTIMA | Top cook takes motorway back to American capital in the most favourable conditions (6) |
| SPIRIT | Vitality seen in the most elevated of characters here (6) |
| LAXEST | Survive former lover turning up in the most easy-going way (6) |
| ATBEST | A most enjoyable time, contained in the most optimistic view (2,4) |
| TAILED | Followed in the most fussy detail (6) |
| SCOTTY | Character played by Simon Pegg in the most recent Star Trek films (6) |
| EVERSO | ___ ___ slightly (In the most minute way possible) |
| DONALD | Disney character in the most films |
| OORT | Dutch astronomer who first postulated the existence of a cloud in the most distant region of the solar system where long-period comets are thought to originate (4) |
| AIDANTURNER | Irish actor whose roles include Ross Poldark in the most recent BBC adaptation of Poldark and Kili in The Hobbit film series |
| CARMINABURANA | Medieval Latin verse anthology found in a monastery in 1803, partly used in the most famous 20th-century cantata |
| WORF | Character who has appeared in the most episodes of the various Star Trek series |
| POLESITTER | Driver in the most favorable position at the start of a race |
| CATCH | The hidden failing in the most eligible bachelor (5) |