| NATO | International security organisation set up (4) |
| SPECTRUM | International security organisation for which Captain Scarlet is an agent in the Gerry Anderson puppet series Captain Scarlet and the Mysterons (8) |
| BOSS | National security organisation in South Africa from 1969-80 (4) |
| GCHQ | British intelligence and security organisation based in Cheltenham, Gloucestershire (inits) (4) |
| ASIO | Security organisation heads held in occasional times as an acronym |
| INTERPOL | International criminal police organisation set up in Vienna in 1923 |
| CIA | US spying organisation set up in 1947 (1,1,1) |
| JAMAICA | Preserve a spy organisation set up for island (7) |
| CHARITY | Organisation set up to help those in need (7) |
| GROAN | Organisation set up an objection (5) |
| MOONWALK | Low, racist organisation set up to conceal source of white dance move (8) |
| AMBULANCE | Organisation set up in 1877 to provide first aid and transport to hospital, St John ... |
| NATIONALTRUST | Organisation set up in Britain in 1895 to preserve open spaces and significant buildings (8,5) |
| SEATO | The regional defence organisation set up by a treaty signed in Manila in 1954, lasting to 1977 (abbrev.) (5) |
| GESTAPO | Nazi organisation set up by Goring in 1933, taken over by Himmler in 1934 (7) |
| AWARD | Duke of Edinburgh's -; youth organisation set up by Prince Philip in 1956 that has since expanded to some 140 countries (5) |
| CHEKA | Soviet secret police organisation set up in 1917, a forerunner of the KGB (5) |
| REARGUARD | Conservative element in an organisation set up distribution of a drug (9) |
| LEAGUEOFNATIONS | Organisation set up after World War I with the intention of preventing future wars (6,2,7) |
| CINEMA | Screen persons caught up in security organisation |