| GLENN | John, the first U.S. astronaut to orbit the earth who later became a senator (5) |
| ALDRIN | Buzz, the second U.S. astronaut to set foot on the moon in 1969 (6) |
| JAY | John, the first chief justice |
| HILLARY | With 36-Across, First Lady who later became a senator from New York |
| GAEA | Greek goddess of the earth, who bore Uranus and by him Oceanus, Cronus and the Titans |
| GAIA | The Greek goddess of the Earth, who bore Uranus (4) |
| MONCK | Originally Cromwell's commander-in-chief in Scotland, the Devon-born soldier who later became a key figure in negotiating the restoration of the monarchy to Charles II in 1660 (5) |
| PEAKE | Author of a series of books set in the crumbling fictional castle Gormenghast; or, the first British ESA astronaut to visit the International Space Station (5) |
| SLEEP | Wayne ---, ballet dancer who later became a judge on ITV's Stepping Out (5) |
| FERMI | Enrico, Italian physicist who constructed the first U.S. nuclear reactor (5) |
| RADIO | In 1922, Warren G. Harding became the first U.S. president to be broadcast over this |
| MANNY | Boxer Pacquiao who later became a Philippine senator |
| YEATS | Literature Nobelist who became a senator in Ireland |
| JOHNGLENN | The first US astronaut to orbit the earth, in 1962, circling it thrice (4,5) |
| LORAX | He told the Once-ler, "Sir! You are crazy with greed. There is no one on earth who would buy that fo |
| TRUMP | The first U.S. president to be impeached twice |
| BIDEN | First president from the first U.S. state |
| STAMP | Benjamin Franklin is depicted on the first U.S. one (1847) |
| NEIL | ___ Armstrong, U.S. astronaut who was first to land on the moon in 1969 (4) |
| LOVELL | Jim, U.S. astronaut who was command module pilot on Apollo 8, the first crewed flight around the Moon (6) |