| ILTROVATORE | Opera by Giuseppe Verdi first performed in 1853 |
| LATRAVIATA | An opera in three acts by Giuseppe Verdi, first performed in Venice in 1853 (2,8) |
| AIDA | Opera in four acts by Giuseppe Verdi, first performed in Cairo in 1871 (4) |
| ERNANI | 1844 opera by Giuseppe Verdi set in Spain in the 16th century |
| IMASNADIERI | 1847 opera by Giuseppe Verdi to a libretto by Andrea Maffei, based on Die Rauber by Friedrich von Schiller |
| FALSTAFF | Opera by Giuseppe Verdi about a Shakespearean character, premiered at La Scala in 1893 |
| RIGOLETTO | Opera by Giuseppe Verdi based on the play Le roi s'amuse by Victor Hugo |
| NABUCCO | The Chorus of the Hebrew Slaves is a piece from this opera by Giuseppe Verdi that premiered in 1842 (7) |
| DONCARLOS | 1867 opera by Giuseppe Verdi (3,6) |
| AMASKEDBALL | English title of an 1859 opera by Giuseppe Verdi (1,6,4) |
| LAFORZADELDESTINO | 1862 opera by Giuseppe Verdi featuring the characters Don Alvaro and Leonora |
| CRANFORD | Episodic novel by Elizabeth Gaskell first published in book form in 1853 (8) |
| TISSOT | Watchmaking company founded in the Swiss city of Le Locle, in the Neuchatel area of the Jura Mountains, in 1853 |
| WURLITZER | American company started by a German immigrant in Cincinnati, Ohio, in 1853 that became famous for its electronic organs and jukeboxes |
| CAYLEY | Engineer who designed a biplane that became the world's first glider to carry a human aloft following a flight by the farmer's reluctant coachman in 1853 (6) |
| STEINWAY | Which piano company was founded in New York in 1853 by a German immigrant? (8) |
| SYRINGE | Medical instrument first developed in 1853 by Charles Gabriel Pravaz and Alexander Wood (7) |
| SOHRABANDRUSTOM | Poem by Matthew Arnold published in 1853 (6,3,6) |
| POSTBOXES | Pillar-shaped structures introduced to Britain by Anthony Trollope in 1853 (9) |
| SOHRABANDRUSTUM | Poem by Matthew Arnold published in 1853 (6,3,6) |
