| HERRIOT | Pen name of arguably world's most famous vet (7) |
| LAURA | Half of arguably the most iconic supercouple of all time |
| LUKE | HALF OF ARGUABLY THE GREATEST SUPERCOUPLE OF ALL TIME |
| DAYTONA | ___ Beach, Florida city once dubbed 'the world's most famous beach' (7) |
| MANDELA | World's most famous political prisoner for 25 years who went on to become the first black president of South Africa, Nelson ... |
| YOKOONO | ____'s husband called her "the world's most famous unknown artist: everybody knows her name, but nobody knows what she does" |
| MONSMEG | World's most famous medieval gun, located at Edinburgh Castle (4,3) |
| RANGERS | They play their home games at 'The World's Most Famous Arena' |
| AGRA | Site of one of the world's most famous onion domes |
| SCALA | One of the world's most famous opera houses, La ... |
| WSS | Initials-sharers of the world's most famous playwright (b.1564 d.1616) |
| SYDNEY | Home to arguably the world's most famous opera house |
| SHAKESPEARE | The world's most famous writer of plays (11) |
| SNOOPY | Fictional beagle who is one of the world's most famous dogs (6) |
| LUCY | Name given to an Australopithecene skeleton found in the Great Rift Valley, the world's most famous hominid fossil (4) |
| PELE | One of the world's most famous athletes, this football (soccer) player helped Brazil win three World Cups |
| CASANOVA | Best known as one of the world's most famous lovers, he also dabbled in espionage |
| AGRAINDIA | City home to the world's most famous mausoleum |
| MSG | It bills itself as "The World's Most Famous Arena": Abbr. |
| MONA | ___ Lisa (world's most famous model) |
