| BY | Preposition expressing relation in space, time, direction or movement |
| INDICES | Ratios expressing relation (7) |
| EVENT | In special relativity, a single point in space-time from which a light cone emanates; or, a planned social or sporting occasion (5) |
| BEYOND | Farther along in space, time or degree (6) |
| WORMHOLE | Hypothetical tunnel in space-time (8) |
| DVANDVA | Diameter over velocity plus volume over area in space-time, say |
| FURTHEST | Most remote in space, time, etc (8) |
| COMET | Body in space time to arrive first (5) |
| REMOTE | Far away in space, time (6) |
| INTO | Preposition expressing direction |
| ASPECT | View in a certain direction; or, position of a garden in relation to the points of a compass (6) |
| GO | A preposition expressing motion to a certain locale |
| AT | A preposition, expressing location (2) |
| CRESCENDO | A gradual increase in loudness or the musical direction or symbol indicating this |
| WITHERSHINS | In a contrary direction or opposite to the direction of the sun (11) |
| ARROW | A mark to indicate a direction or relation (5) |
| SKEWED | Having an oblique or slanting direction or position (6) |
| UPALONG | Dialect term meaning in a particular direction, or towards a larger community |
| ENLIST | In one direction or another, lean towards move to join up (6) |
| ONE | Word before Direction or Republic in band names |