| JEB | Son and brother of George |
| JEBBUSH | Son and brother of George |
| IRA | Forename of the songwriting partner and brother of George Gershwin (3) |
| ORBS | Eyes son and brother from the back |
| LAERTES | Named after the father of Odysseus, the son of Polonius and brother of Ophelia in Hamlet (7) |
| EREBUS | In Greek mythology, the god of darkness, son of Chaos and brother of Night |
| ORESTES | Son of Agamemnon and Clytemnestra and brother of Electra (7) |
| APOLLO | In classical mythology, son of Zeus and Leto and brother of Artemis (6) |
| ESAU | In the Old Testament, son of Isaac and Rebecca and brother of Jacob |
| BEAU | Actor son of Lloyd and brother of Jeff, ___ Bridges |
| SPAIN | Where former Weatherfield resident Andy McDonald, son of Liz and brother of Steve, now lives (5) |
| ELI | Son of Archie and brother of Peyton, in football's Manning family |
| HERMOGENES | Ancient Athenian philosopher who was the son of Hipponicus and brother of Callias |
| JUDE | Penultimate book of the New Testament, written by 'a servant of Jesus Christ and brother of James' (4) |
| EMILIO | _ Estevez, son of Martin and brother of Charlie Sheen (6) |
| LAERTEU | Son of Polonius and brother of Ophelia in Shakespeare's Hamlet 1601 |
| HORSA | According to tradition, a 5th Century warrior and brother of Hengist, who took part in the invasion and conquest of Britain (5) |
| OTUS | Son of Poseidon and brother of Ephialtes in Greek mythology |
| DEMETRIUS | Son of Queen Tamora and brother of Chiron in Shakespeare's Titus Andronicus (9) |
| HENGIST | Warrior from the 5th century and brother of Horsa, who took part in the invasion and conquest of Britain (7) |
