| BALBOA | Spanish discoverer of the Pacific, 1513 |
| GALILEO | Forename of the discoverer of the isochronism of a pendulum who improved upon the design of the refracting telescope to observe the four largest moons of Jupiter (7) |
| ROBERT | Forename of either the polymath discoverer of the law of elasticity, the inventor of the Bunsen burner or the Royal Society co-founder regarded as the first modern chemist (6) |
| ARNE | ___ Saknussemm, discoverer of the center of the earth in "Journey to the Center of the Earth" |
| DOPPLER | Discoverer of the effect of relative speed on the observed frequency of waves |
| CRICK | Co-discoverer of the contents of the circled letters |
| WATSON | Co-discoverer of the contents of the circled letters |
| CABOT | Surname of the discoverer of the North American mainland (5) |
| ALIBABA | Discoverer of the treasure of the Forty Thieves |
| CASSINI | Discoverer of the division in the rings of Saturn after whom a space probe (with Huygens) is co-name |
| HOOKE | Discoverer of the law of elasticity whose folio volume Micrographia illustrated with copperplate engravings was an early book published by the Royal Society (5) |
| THOMSON | J. J. -; discoverer of the electron whose son George co-discovered the diffraction of electrons by crystals (7) |
| CECIL | Biographer born at Hatfield House in 1902, whose spymaster ancestor, Robert, 1st Earl of Salisbury, was the principal discoverer of the Gunpowder Plot (5) |
| DIAS | Discoverer of the Cape of Good Hope |
| EULER | Discoverer of the law of quadratic reciprocity |
| KEPLER | Johannes -; discoverer of the three laws of planetary motion (6) |
| FLORIDA | US state named by Spanish explorer Ponce de Leon in 1513, the name meaning 'full of flowers' (7) |
| FLODDENFIELD | Site of the 1513 battle in which King James IV of Scotland was killed (7,5) |
| EIGHTH | Henry the ___ , English Tudor monarch in whose reign the Battle of Flodden took place in 1513 (6) |
| FLODDEN | Battle of 1513 in Northumberland in which the English gained victory over the Scots (7) |
