| PERCEVAL | Spencer _, the only British Prime Minister to have been assassinated (8) |
| SPENCER | The only British Prime Minister to have been assassinated, ... Perceval |
| TWENTYSIX | How many popes have been assassinated? (6-3) |
| ANDREWBONARLAW | The only British Prime Minister to have been born outside the British Isles (6,5,3) |
| WINSTONCHURCHILL | The only British prime minister to receive the Nobel Prize for Literature |
| DISRAELI | Only British prime minister of Jewish birth |
| PITCAIRN | ____ Islands, the only British Overseas Territory in the Pacific Ocean (8) |
| SCOTLAND | Only British team yet to win the Six Nations rugby championship (8) |
| NETANYAHU | Only Israeli prime minister to have been elected three times in a row (9) |
| THATCHER | Artisan who makes roofs from long straw, wheat straw or water reed; or, the prime minister to be portrayed by Gillian Anderson in series four of The Crown (8) |
| WHITELAW | William, Conservative politician who served as deputy prime minister to Margaret Thatcher (8) |
| CHANAKYA | Prime Minister to Chandragupta Maurya (8) |
| MATTHEWS | Spencer _, former Made In Chelsea star married to Vogue Williams (8) |
| ASQUITH | Known as HH, the only UK prime minister to have taken office on foreign soil (7) |
| MCKINLEY | Third president to be assassinated |
| GARFIELD | Second president to be assassinated |
| POSTMERIDIEM | Late in the day for British prime minister to be so short (4,8) |
| KEEGAN | Who is the only British player to have been voted European Footballer of the Year twice? (6) |
| PALMERSTON | Viscount, the last British Prime Minister to die while in office (10) |
| EDWARDVIII | King for less than a year as he stepped down to marry Wallis Simpson; the only British sovereign to abdicate voluntarily (6,1,1,1,1) |
