| PUDDINGLANE | Street where the Great Fire of London originated in 1666 (7,4) |
| PUDDING | ____ Lane, site of a bakery where the Great Fire of London began in 1666 (7) |
| CHRISTOPHER | English architect who designed St Paul's Cathedral, in the English Baroque style, after the Great Fire of London (11,4) |
| BAKERY | Shop where the great fire of London started (6) |
| MISANTHROPE | The ___, 1666 play by Moliere subtitled The Cantankerous Lover (11) |
| EVELYN | Author of a posthumously published diary describing events of 1665-6 including the Great Plague and the Great Fire of London (6) |
| WREN | Architect responsible for rebuilding over 50 churches in the City of London after the Great Fire of 1666 (4) |
| GREATPLAGUE | Major epidemic from 1665 to 1666 (5,6) |
| PRIVET | Shrub often used for hedging in neat suburban gardens, hence its use as the name of a muggle street, where the non-magical "perfectly normal" Dursleys reside, in the fictional universe of Harry Potter |
| STAIR | One of 311 at the Monument to the Great Fire of London |
| STPAULS | Abbreviated name of the London cathedral redesigned by Sir Christopher Wren following its destruction by fire in 1666 (2,5) |
| GREATFIRE | Short name of a major disaster that occurred in London in 1666 (5,4) |
| GRATE | Where the Great Fire is said to have started? |
| CHEESE | Among the belongings rescued by Samuel Pepys during the Great Fire of London, dairy food once measured in weys, used for rarebit, fondue or ploughman's lunches (6) |
| PARMESAN | Type of cheese which Samuel Pepys buried in his garden during the Great Fire of London (8) |
| SIXTEENSIXTYSIX | Year of the Great Fire of London (7,8) |
| SIRCHRISTOPHER | Designer of St. Paul's Cathedral, after the Great Fire of London (3,11,4) |
| CHRISTOPHERWREN | Astronomer, mathematician, physicist and architect who was credited with rebuilding 52 churches after the 1666 Great Fire of London (11,4) |
| PEPYS | Samuel who chronicled the Great Fire of London |
| SAMUEL | Pepys whose diary chronicled the Great Fire of London |