| SOREST | Suffering the most discomfort, therefore take a break (6) |
| HEARTBURN | Discomfort so-called 11-acrosses of 28-across? (9) |
| EASTER | You need a rest at this point so take a holiday (6) |
| EXHALE | In it goes to heal - so take a breather! (6) |
| INHALE | In it goes to heal - so take a breather! (6) |
| OGRESS | Monstrous woman's back. Therefore take steps round the edge |
| TIMEOUT | Watch is slow - so take a break (4,3) |
| IGNORE | There's nothing in changing a rule, so take no notice (6) |
| CRUTCH | So take the stick if it provides support. (6) |
| EUREKA | Victorian battle orders to duke - so take care (6,8) |
| LISTEN | Lost one gun, so take notice (6) |
| BELONG | Have owners, so take your time (6) |
| ITEASY | Eagles "So open up, I'm climbin' in, so take ___" |
| TUNDRA | It's frozen so take notice and turn away |
| ENGORGE | Overeat, so take a little ginseng or get obese |
| THROUGHTHENOSE | So take a breath and pay? (7,3,4) |
| JETLAGGED | Suffering the effects of a long flight (3-6) |
| SOBERED | Down from a high, therefore take leftist stance (7) |
| PAINTER | One who has a brush with suffering, the centrepiece of investiture with Queen |
| OUTSMART | Although suffering the wrong kind of stinging pain, could outplay the rest (8) |