| YOGHURT | The main component of tzatziki (7) |
| RAITA | Indian version of tzatziki (5) |
| STIGMA | Spot Greek character eating a bit of tzatziki (6) |
| AMMONIA | One of the main components of Jupiter's atmosphere, this compound is a colourless, pungent gas composed of nitrogen and hydrogen (7) |
| SUCROSE | A compound that is the main component of cane sugar (7) |
| VAGUS | From the Latin for "wandering", the body's 10th cranial nerve and the main component of the parasympathetic nervous system (5) |
| IRON | Metal that is the main component of the Earth's inner core (4) |
| SILICA | What is the main component of glass? (6) |
| ACETIC | _ acid, the main component of vinegar apart from water (6) |
| VERMOUTH | One of the main components of a Martini cocktail (8) |
| CUTIN | Waxy water-repellent polymer that forms the main component of plant cuticle (5) |
| SILICON | Element whose dioxide is the main component in glass (7) |
| METHANE | Main component of natural gas (7) |
| LADDERS | What is the other main component of a board game containing snakes |
| PLATOON | Climbing mountain, main components of air have to part company (7) |
| OVERANDOVER | Repeatedly, or what can come before the main components of 17-, 30-, 39-, or 46-Across |
| DNA | Main component of chromosomes (1,1,1) |
| CELLULOSE | Main component of plant fibres (9) |
| SULFUR | Main component of skunk spray |
| TALC | Main component of soapstone |
