| LEO | The world's first business computer (3) |
| EXEC | River Clyde's first business leader (4) |
| HERB | A lady's first business may go to pot (4) |
| COHERE | In this place first business concern will be consistent (6) |
| EYE | The ___ of the World, first book in The Wheel of Time (3) |
| FUN | First word across in the world's first crossword (1913) |
| EVE | The world's first lady? (3) |
| RCA | Co. that launched the world's first communications satellite |
| WAR | Clinton has approved a treaty to create the world's first permanent ___ crimes court |
| TREVITHICK | Ding Dong mine engineer who invented the Puffing Devil and built the world's first steam railway locomotives including the Catch Me Who Can and the Penydarren (10) |
| ADALOVELACE | British mathematician and Lord Byron's daughter, dubbed the world's first computer programmer (3,8) |
| SPUTNIK | Name for the world's first satellite, launched by the Soviet Union on October 4, 1957, and the name of any of a series of three artificial Earth satellites. (7) |
| MUNGOMAN | In 1974, the geomorphologist Jim Bowler discovered these remains while studying the climate of prehistoric Australia. They are 40,000 years old and are the world's first known human ritual burial. Wha |
| DRIVERLESSBUS | What was the World's first, to go over the Forth Road Bridge? (10,3) |
| LOVELACE | Considered the world's first computer programmer |
| LEMANS | The world's first purpose built motor-racing circuit opened for the French Grand Prix in this town |
| LUMIERE | Brothers who patented the cinematograph, considered the world's first film-makers (7) |
| EIGG | Small Isle of the Inner Hebrides along with Canna, Rum and Muck; site of the world's first electricity grid powered exclusively from renewable energy (4) |
| TELE | Made by Fender, the common name of the world's first commercially successful solid-body electric guitar (4) |
| PILSENER | Pale lager with the unique claim to being the world's first golden beer |