| ELIASHOWE | US inventor awarded a patent in 1846 for his lockstitch sewing machine (5,4) |
| RUNG | Like the Liberty Bell in 1846, for the last time |
| HOWE | US inventor who patented the world's first lockstitch sewing machine (4) |
| CAMBRIDGE | A university city in Massachusetts (pop about 105,000), incorporated in 1846 (9) |
| ELIZABETH | And 25. Poet who secretly married Robert Browning in 1846 (9,7) |
| IDEAOWNER | Person pursuing a patent, perhaps |
| COPYRIGHT | Ape correct to get a patent (9) |
| ELIAS | Howe who patented the lockstitch sewing machine |
| EDISON | Which inventor (Thomas ___) took out more than a thousand patents in his lifetime? (6) |
| COMPLAINED | Detective after patent in advance, made a formal accusation (10) |
| BIPEDS | Upstanding characters are as patent in the county (6) |
| POPUP | What toaster innovation did American Charles P Strite patent in 1921? (3-2) |
| CHAINSAW | What cutting device did Andreas Stihl patent in 1926? (8) |
| IBM | Tech company that was granted a record 9 262 patents in 2019 |
| SPEC | Informal or short word either for a technical standard or a description of an invention for which a patent is sought (4) |
| ELEVATOR | What did Elisha Otis patent in 1853? (8) |
| DYNAMITE | What did Alfred Nobel patent in 1866? (8) |
| PASTURESTREET | Location of a level crossing in Grimsby, where a terminus for the East Lincolnshire Railway was originally planned in 1846 (7. 6) |
| ZEISS | German optician who opened a lens workshop in Jena in 1846 that developed into a company specialisin |
| SMITHSONIAN | Foundation for education and scientific research in Washington, DC, US, established in 1846 (11,11) |