| BREATHLESS | Vitally in need of inspiration! |
| NOSTRIL | Get a hole in the head? Some may find that a source of inspiration! (7) |
| IMPERATIVE | Vitally important |
| AERATOR | A daughter of Mnemosyne, right one to provide inspiration! (7) |
| TRENDSETTING | Retirement finally, Roger, stop compiling crosswords, giving others inspiration! |
| WHATCANBEDONE | Are you serious that it's possible? Sounds like a question looking for inspiration! (4,3,2,4) |
| HEARTLAND | Vitally important area later developed in consequence of deal? (9) |
| CRISIS | What is a vitally important stage in the course of something (6) |
| ESSENTIALLY | Yes, all set in making changes in a vitally important way (11) |
| CARDINALNEWMAN | Vitally important neophyte, 16 of the 18 3 (8,6) |
| OFLIFE | Vitally piquant description of variety! (5,2,4) |
| SPICE | Vitally piquant description of variety! (5,2,4) |
| INSTRUMENTAL | Vitally involved in ordering terminal nuts (12) |
| OVERHEATS | ...of vitally starting to enter transitioning, or the sea warms excessively |
| GASMASK | One could be faced with this protection against dangerous inspirations! (3-4) |
| ORGAN | Vitally functioning part of a creature (and a large musical instrument!) (5) |
| BARBARACARTLAND | Writer spoke twice with Bill, replacing that man in vitally important area (7,8) |
| LIFEANDDEATH | Vitally important (matter) (4,3,5) |
| ESSENTIAL | Absolutely necessary; vitally important (9) |
| INDISPENSABLE | Vitally important, like something the pharmacist can't offer? |
