| EMPLOYMENT | What's the use of working? |
| WORRYING | "What's the use of ___ ?" |
| AVAIL | What's the use of a Valentine if one is included in it? (5) |
| WHYBOTHER | "What's the use?" |
| ALOST | "It's _ cause!" (What's the use?) |
| FUTILEISM | Social system under which all feel "what's the use?" |
| GLORY | "So what's the use between death and", from Babyshambles' "Fuck Forever" (5) |
| ORGANIC | Form of farming lobbied by the Soil Association based on a set of standards that includes cutting the use of pesticides, chemical fertilisers and antibiotics (7) |
| ETCHING | Work of art created with a printmaking technique involving the use of acid, drypoint or engraving, such as any one of the many by Rembrandt (7) |
| RESERVATION | Tract of land set aside for the use of Native Americans after the rest of their traditional land had been taken over |
| PUBLICITY | The process of attracting attention to people and products by the use of the media (9) |
| RUFIYAA | Succeeding the use of cowry shells and printed on decorative banknotes, the currency of the Maldives (7) |
| MAGIC | The art of producing illusions as entertainment by the use of sleight of hand (5) |
| FAHRENHEIT | What was the surname of the German instrument-maker who pioneered the use of mercury? (10) |
| NOTEBOOK | The use of ____s by the police is controlled by the Freedom of Information act passed in 2000 |
| PEA | "Ella Minnow ___" (2001 novel in which the government bans the use of more and more letters of the alphabet) |
| KINECT | Device for the Xbox 360, allowing users to play games with the use of their own body as the game con |
| FAUVISM | An artistic movement of the early 20th Century, characterised by the use of bright colours and simplified forms (7) |
| NEWSTYLE | Method of reckoning that superseded the use of the Julian calendar (3,5) |
| CHOIRSTALLS | Rows of seats in a church for the use of the church singers or clergy (5,6) |