| ALMAGEST | Work on astronomy by Ptolemy containing a description of the geocentric system of the universe and a star catalogue |
| GRAMMAR | The morphology and syntax of a language; a book containing a description of said linguistry; or, the basic rules of a field of knowledge (7) |
| PTOLEMY | Alexandrian astronomer who proposed a geocentric system that was undisputed until the late Renaissance (7) |
| COSMOS | Ordered system of the Universe (6) |
| COX | Presenter of numerous BBC science programmes including Wonders of the Universe and Forces of Nature. (3) |
| ALECBALDWIN | It's Complicated actor who narrated the scientific documentaries Journey to the Edge of the Universe and Frozen Planet: 2 wds. |
| FORTYTWO | Number that's the answer to the Ultimate Question of Life, the Universe and Everything, in "The Hitchhiker's Guide to the Galaxy" |
| ANSWER | - to the Ultimate Question of Life, the Universe, and Everything; number 42 in The Hitchhiker's Guide to the Galaxy (6) |
| LAZER | Major ---, electronic band that has released the albums Free The Universe and Peace Is The Mission ( |
| SAGITTA | From the Latin meaning "arrow" and listed by Ptolemy in the 2nd century, one of the constellations i |
| FAINTLY | "as he heard the snow falling ... through the universe and ... falling" (James Joyce) |
| OGDEN | Linguist and philosopher who created Basic English as a simplified system of the English language based on 850 words (5) |
| GULAG | Which penal system of the Soviet Union consisted of a network of labour camps? (5) |
| DOUGLASADAMS | Author of Life, the Universe and Everything (7,5) |
| SCIFI | Some terrific stuff in retrospect: like Life, the Universe and Everything? (3-2) |
| ROOTAGE | A developed system of the underground parts of a plant (7) |
| VEINS | Vessels forming part of the blood circulatory system of the human body (5) |
| SKY | The at Night long-running BBC documentary series on astronomy, presented by Sir Patrick Moore from 1957 to 2013 (3) |
| LETITIAWRIGHT | Actress who plays Shuri in the Marvel Cinematic Universe and has been on Black Mirror: 2 wds. |
| ANTHONYMACKIE | Actor who plays Falcon in the Marvel Cinematic Universe and has been on Black Mirror: 2 wds. |
