| LEONA | _ Lewis, singer who was the first female winner of The X Factor (5) |
| CURIE | Who became the first female winner of a Nobel Prize in 1903? (5) |
| SELMALAGERLOF | Swedish author who was the first female winner of the Nobel Literature Prize in 1909 (5,8) |
| HURTLOCKER | Movie with the first female winner of the Oscar for Best Director, with "The" |
| RACHELWHITEREAD | Artist who became the first female winner of the Turner prize, for House in 1993 |
| GRANT | Linn ..., the DP World Tour's first female winner. (5) |
| THEAGEOFINNOCENCE | 1920 novel which made Edith Wharton the first female winner of the Pulitzer prize for literature |
| NADIA | ..... Comaneci, in gymnastics, female winner of five Olympic gold medals (5) |
| NEHRU | His sister, Vijaya Lakshmi Pandit, was the first female president of the U.N. General Assembly |
| LIDIA | Tejada who was the first female president of Bolivia |
| ASTOR | Viscountess who was the first female MP to take her seat |
| WYATT | She was the first female mayor of St. John's, Newfoundland |
| EVERT | Chris who was the first female athlete to host "Saturday Night Live" |
| BARBRA | _ Streisand, first female winner of the Best Director Golden Globe (6) |
| KATE | _ Lawler, the first female winner of Big Brother on Channel 4 (4) |
| FRENCH | The Suzanne Lenglen Cup is given to the female winner of The ___ Open. (6) |
| FACES | Female winners at Wimbledon becoming well-known people (5) |
| LAWLER | First female winner of Big Brother, Kate _ (6) |
| SHAYNE | Actor and singer who was the second winner of The X Factor, _ Ward (6) |
| HINGIS | Martina ..... is the youngest female winner of a Grand Slam title in the Open Era. (6) |
